PhD Researcher in Computational Cancer Biology
4 weeks ago
We are seeking a highly motivated and talented PhD researcher to join our team at the University of Oulu's ECM-Hypoxia Research Unit. As a PhD researcher, you will participate in the national 1000 doctorates pilot programme, which supports the completion of a doctoral degree within three years.
Cancer initiation and progression depend on the interplay between heterogeneous tumor cells and the surrounding tumor microenvironment (TME). Our research focuses on understanding the composition and roles of tumor ECM compartments (niches) in modulating cancer cell phenotypes and fates, cancer progression and therapy resistance, at the systems biology level.
You will work closely with our team to develop machine learning/AI algorithms to deconvolute the connections between ECM niches and functional cancer cell states at the single-cell, spatial, and proteomics level. These algorithms will help identify druggable ECM targets in cancer, which will be validated in our cellular and in vivo cancer models.
As a member of our team, you will have access to a network of numerous national and international collaborations, which will expose you to state-of-the-art methodologies for ECM research and offer rich opportunities for internships, mobility, and further career development after completion of the PhD in three years.
Requirements- Master's or equivalent degree in bioinformatics, biostatistics, data analysis, molecular and cell biology, biochemistry, biomedicine, medicine, or related fields
- Excellent command of R and/or Python and advanced knowledge of machine learning and deep learning
- Experience with big data analysis (bulk and single-cell RNASeq, proteomics, spatial methods are considered an advantage)
- Basic knowledge of cancer cell biology
- Fluent in written and spoken English language
- Excellent communication and teamwork skills
- Full dedication on the research project and ability to meet project deadlines
- A dynamic research environment which promotes personal and professional growth as a scientist
- The support of two experienced, enthusiastic and multidisciplinary research teams
- A low hierarchy structure focused on teamwork and constant discussion flow
- An inspiring international research atmosphere and smooth entry to national and international ECM research networks
- Structured, interdisciplinary doctoral training
- We have a HR Excellence in Research -quality label which is a recognition awarded by the European Commission for the development of researchers' working conditions and careers
- Finland is one of the most livable countries in the world, with a high quality of life, safety, excellent education system, and competitive economy
Applications, together with all relevant enclosures, should be submitted using the electronic application form. The application should be written in English and include the following:
- Certificates/Diplomas Scanned copy of the original relevant Master's degree certificates and transcript of records and, when necessary, official translations to Finnish or English
- A motivation letter (max. 2 pages) summarizing applicant's professional experience and expertise and describing why the applicant is a good fit for this position
- Curriculum vitae (max. 2 pages)
- Research plan (max. 4 pages)
- A valid certificate or other demonstration of language proficiency
Only applications containing all relevant appendices and submitted through the online recruitment system will be considered.
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